Nicotinamide Adenine Dinucleotide

What is NAD?

NAD (Nicotinamide Adenine Dinucleotide) is a vital coenzyme naturally present in every living cell. It plays a crucial role in numerous biological processes that sustain life, including energy metabolism, DNA repair, cell signaling, and gene expression regulation.

NAD exists in two forms — NAD⁺ (oxidized) and NADH (reduced) — which work together to transfer electrons in metabolic reactions. This process is essential for converting nutrients like carbohydrates, fats, and proteins into usable energy (ATP) that powers cellular functions.

Beyond energy production, NAD also supports the activity of important enzymes such as sirtuins and PARPs, which are directly involved in cellular repair, stress resistance, and longevity. These enzymes help maintain the integrity of DNA, promote healthy cellular communication, and regulate the body’s response to inflammation and oxidative stress.

However, NAD levels naturally decline with age, stress, and unhealthy lifestyle factors, leading to reduced energy, slower metabolism, cognitive decline, and weakened immune defense.

Supplementing with NAD or NAD precursors (such as NMN or NR) can help replenish cellular NAD levels, supporting:

• Healthy aging and longevity

• Enhanced energy metabolism

• Improved cognitive function and memory

• Stronger immune system

• Better cellular repair and resilience